ACE Technology Guidances communicate recommendations from the MOH Drug Advisory Committee or the MOH Medical Technology Advisory Committee on the subsidy status and appropriate use of drugs, vaccines or medical technologies that have been evaluated by ACE. The guidances also include the Committee’s rationale for the subsidy recommendations, and key clinical and economic evidence which informed their deliberations. Plain English Summaries (PES) to explain ACE Technology Guidances are available for patients and the public.

Published on 23 Mar 2020
Last Updated on 31 Jan 2022
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Guidance Recommendations
The Ministry of Health Medical Technology Advisory Committee has recommended:
  • Continuous subcutaneous insulin infusion therapy (CSII) and its consumables as a treatment option for adults and children with type 1 diabetes mellitus:
    • who use multiple daily injections of insulin (MDI) to achieve target HbA1c but result in the person experiencing disabling hypoglycaemia, where disabling hypoglycaemia is defined as the repeated and unpredictable occurrence of hypoglycaemia that results in persistent anxiety about recurrence and is associated with a significant adverse effect on quality of life (QoL); or
    • who have unacceptably high HbA1c (i.e. at 8.5% or above) on MDI despite a high level of care, where a high level of care refers to patient adherence to structured education programmes provided by a multidisciplinary team at specialist outpatient clinics in the public healthcare sector, which comprise an endocrinologist with a special interest in CSII, a diabetes nurse educator, and a dietician; or
    • where MDI is not clinically suitable and acceptable for children younger than age 12 years, and where careful consideration is made jointly by the multidisciplinary healthcare team, the children, and their caregivers who are responsible for supervising them in using CSII instead of MDI.
  • CSII should be discontinued if it does not result in a sustained improvement in glycaemic control as evidenced by a fall in HbA1c levels or an increase in time-in-range blood glucose readings, or a sustained improvement in disabling hypoglycaemia, or a sustained improvement in QoL.

Subsidy status

CSII subsidies for the abovementioned indications apply only to the CSII device and its consumables listed in the Annex.

CSII Medical Technology Guidance (as of 1 Feb 2022) Medical technology guidance CSII Annex (as of 1 Feb 2022) (2)