Review of cancer drugs for previously treated multiple myeloma

Published on 04 Jan 2022
Last Updated on 01 Nov 2025

Guidance Recommendations

The Ministry of Health's Drug Advisory Committee has recommended:

• Carfilzomib 30 mg powder for solution for infusion;

• Ixazomib 3 mg and 4 mg capsules; and

• Pomalidomide 1 mg, 2 mg, 3 mg and 4 mg capsules

for previously treated multiple myeloma in line with specific clinical criteria.

Carfilzomib, ixazomib and pomalidomide should be used in line with the recommended treatment regimens listed in the Annex.

Subsidy status

Carfilzomib 30 mg powder for solution for infusion, ixazomib 3 mg and 4 mg capsules and pomalidomide 1 mg, 2 mg, 3 mg and 4 mg capsules are recommended for inclusion on the Medication Assistance Fund (MAF) in line with the abovementioned indication.

MAF assistance for carfilzomib will be implemented from 4 January 2022. MAF assistance for ixazomib and pomalidomide will be implemented from 1 September 2022.

MAF assistance does not apply to daratumumab 100 mg/5 ml and 400 mg/20 ml concentrate for solution for infusion and 1800 mg/15 ml solution for subcutaneous injection when used for previously treated multiple myeloma.

Clinical indications, subsidy class and MediShield Life claim limits for all drugs included in the evaluation are provided in the Annex.

Review of cancer drugs for previously treated multiple myeloma (Updated 1 Nov 2025) [PDF, 192 KB]

PES Cancer drugs for previously treated multiple myeloma (Published 4 Jan 2022) [PDF, 159 KB]